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FT-NIR process analyzer for pharmaceutical and life sciences industries

FTPA2000-260PH

The FTPA2000-260PH is a multi-point FT-NIR analyzer designed for remote, real-time monitoring of continuous and batch processes in pharmaceutical and life sciences industries. This versatile analyzer is fully validatable and allows to develop methods for monitoring of product Critical Quality Attributes (CQAs). 

 

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Overview

It is also the ideal solution for implementation of process analytical technology (PAT) in manufacturing environment, as part of Quality by Design (QbD) initiatives. The instrument can be located in a general purpose area or in a cabinet supplied by ABB and certified for hazardous area.

Some of the main features of the FTPA2000-260PH are:

  • Multi-channel capability (up to 8 channels)
  • Possibility to monitor several properties or CQAs simultaneously
  • Remote analysis with fiber optics (up to 80m for solids and 300m for liquids)
  • Fully unattended and automated operations driven by ABB process control software FTSW
  • On-the-fly diagnostics on instrument and process status
  • Real-time connectivity to plant IT and control systems (OPC, Modbus or 4-20mA)
  • Protection of electronic records as per FDA’s CFR21 P11 requirements
  • Flexible sampling (cells/probes, reflection/transmission)
  • All accessories can be used in EX-rated environment

 

Data

ABB guarantees transferability of methods between its instruments. Any part of the FTPA2000-260PH system can be serviced or replaced without having to modify the method and with no loss of accuracy, even the fiber optic cables and sampling systems. This is due to the ultra-high precision manufacturing methods used and the extreme stability of the laser controlled spectral encoding process. As a result, the absorbance reproducibility between units approaches the instrument repeatability on single unit. 

Flexible sampling
The use of fiber optic cables permits to locate the analyzer in any general-purpose area, isolated from hazardous materials and environments, thus significantly reducing civil engineering costs. The FTPA2000-260PH makes use of this advantage to add flexibility in implementation.

The FTPA2000-260PH includes a multi-detector module and has ample throughput to simultaneously illuminate several fiber optic bundles. Signals from the detector’s module are electronically multiplexed and use non-moving parts. This provides outstanding repeatability and allows a single analyzer to continuously monitor up to eight different sampling points without suffering from the performance and reliability issues traditionally associated with opto-mechanical multiplexers.

 

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